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Artificial groundwater recharge 1

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Cell migration 1

Class one integrons 1

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Fifty Years of Water Sensitive Urban Design, Salisbury, South Australia

John C. Radcliffe, Declan Page, Bruce Naumann, Peter Dillon

Frontiers of Environmental Science & Engineering 2017, Volume 11, Issue 4, doi: 10.1007/s11783-017-0937-3

Abstract: Managed aquifer recharge was introduced for storing remediated low-salinity stormwater by aquifer storageand recovery (ASR) in a brackish aquifer for subsequent irrigation.

Keywords： Managed Aquifer Recharge (MAR)     Stormwater harvesting     Water recycling drinking water     Low impact development    

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Quantification of seepage in a multi-layered disconnected river-aquifer system

Jiang LI, Haizhu HU, Xiaomin MAO, Yi LIU

Frontiers of Agricultural Science and Engineering 2017, Volume 4, Issue 2,   Pages 237-245 doi: 10.15302/J-FASE-2017135

Abstract: Quantification of seepage in disconnected river-aquifer systems is significant for local water managementlow permeability layers (including but not limited to the liners) in multi-layered disconnected river-aquiferA case study was conducted in the Yongding River with river-aquifer seepage calculated under variousmethod was reliable and convenient for calculating long-term, large area seepage in disconnected river-aquifer

Keywords： infiltration     low permeability liner     multi-layered porous media     river-aquifer seepage    

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CHALLENGES PROVIDING MULTIPLE ECOSYSTEM BENEFITS FOR SUSTAINABLE MANAGED SYSTEMS

Frontiers of Agricultural Science and Engineering 2022, Volume 9, Issue 2,   Pages 170-176 doi: 10.15302/J-FASE-2022444

Abstract:

Since humans started practicing agriculture at the expense of natural forests, 8000 years ago, they have affected atmospheric CO2concentrations. Their impact on atmospheric CH4 started about 5000 years ago, as result of the cultivation of paddy rice. A challenge of modern agricultural practices is to reverse the impact cropping has had on greenhouse gas emissions and the global climate. There is an increasing demand for agriculture to provide food security as well as a range of other ecosystem services. Depending on ecosystem management, different practices may involve trade-offs and synergies, and these must be considered to work toward desirable management systems. Solution toward food security should not only focus on agricultural management practices, but also on strategies to reduce food waste, more socially-just distribution of resources, changes in lifestyle including decarbonization of the economy, as well as reducing human population growth.

Keywords： crop diversification / ecosystem services / food security / sustainable cropping systems    

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Nanosized magnetite in low cost materials for remediation of water polluted with toxic metals, azo- and antraquinonic dyes

María Fernanda HORST,Verónica LASSALLE,María Luján FERREIRA

Frontiers of Environmental Science & Engineering 2015, Volume 9, Issue 5,   Pages 746-769 doi: 10.1007/s11783-015-0814-x

Abstract: Nanosized magnetite has emerged as an adsorbent of pollutants in water remediation. Nanoadsorbents include magnetic iron oxide and its modifiers/stabilizers, such as carbon, silica, clay, organic moieties (polymers, aminoacids, and fatty acids) and other inorganic oxides. This review is focused on the recent developments on the synthesis and use of magnetic nanoparticles and nanocomposites in the treatment of contaminated water. The emphasis is on the influence of the iron oxide modifiers on some properties of interest such as size, BET area, and magnetization. The characteristics of these nanomaterials are related to their ability to eliminate heavy metal ions and dyes from wastewater. Comparative analysis of the actual literature was performed aiming to present the magnetic material, its preparation methodology and performance in the elimination of the selected pollutants. Vast information has been properly summarized according to the materials, their properties and preferential affinity for selected contaminants. The mechanisms governing nanomaterial’s formation as well as the interactions with heavy metals and dyes have been carefully analyzed and associated to their efficiency.

Keywords： nanomagnetite     water remediation     toxic metals     dyes     supported magnetite    

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Production of pectic extracts from sugar beet pulp with antiproliferative activity on a breast cancer cell line

Jacqueline CONCHA, Caroline WEINSTEIN, María Elvira Zú?IGA

Frontiers of Chemical Science and Engineering 2013, Volume 7, Issue 4,   Pages 482-489 doi: 10.1007/s11705-013-1342-5

Abstract: In the last years, sugar beet pectins have been the subject of several investigations involving extraction methodologies, chemical composition and functional properties. The structure of pectins, which depends on the extraction method, is decisive in their capacity to induce apoptosis on several cancer cell lines like colon, prostate and breast. In this work, sugar beet pectin extraction was performed in the following steps: lipid extraction with hexane, removal of soluble complex carbohydrates and proteins, and enzymatic treatment with amyloglucosidase, protease, and pectinase. The enzymatic treatment was carried out with Rohapect DA6L under the following conditions: 50°C, pH 4.0, 2% enzyme/substrate (E/S) ratio, 15 h, and a solid to liquid ratio of 1 ∶ 10. The pectic extract showed a degree of polymerization (DP) profile of 55.8% with DP≥7; 4.9% with DP6; 5.8% between DP2 and DP6 ; 4.7% with DP2; and 28.8% with DP1. The pectic extract was examined for its antiproliferative activity on the MCF-7 breast cancer cell line. At a concentration range of 12.5–25 mg/mL the pectic extract killed 80.6% of the cells, exhibiting a higher antiproliferative activity than 4-hydroxytamoxifen (4-OHT), a classical anticancer drug, which killed 56.5% of the cells.

Keywords： pectic extracts     antiproliferative activity     breast cancer     enzymatic treatment    

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The Fibrillar Matrix: Novel Avenues for Breast Cancer Detection and Treatment Review

Rasha Rezk,  Raquel Marín-García,  Annica K.B.Gad

Engineering 2021, Volume 7, Issue 10,   Pages 1375-1380 doi: 10.1016/j.eng.2021.04.024

Abstract:

Breast cancer is marked by large increases in the protein fibers around tumor cells. These fibers increase the mechanical stiffness of the tissue, which has long been used for tumor diagnosis by manual palpation. Recent research in bioengineering has led to the development of novel biomaterials that model the mechanical and architectural properties of the tumor microenvironment and can be used to understand how these cues regulate the growth and spread of breast cancer. Herein, we provide an overview of how the mechanical properties of breast tumor tissues differ from those of normal breast tissue and non-cancerous lesions. We also describe how biomaterial models make it possible to understand how the stiffness and viscosity of the extracellular environment regulate cell migration and breast cancer metastasis. We highlight the need for biomaterial models that allow independent analysis of the individual and different mechanical properties of the tumor microenvironment and that use cells derived from different regions within tumors. These models will guide the development of novel mechano-based therapies against breast cancer metastasis.

Keywords： Breast cancer     Tissue stiffness     Cancer metastasis     Cell migration     Bioengineered scaffold     Viscosity    

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Multifunctional antimicrobial chlorhexidine polymers by remote plasma assisted vacuum deposition

Aparicio, María Alcaire, Carmen López-Santos, Juan P.

Frontiers of Chemical Science and Engineering 2019, Volume 13, Issue 2,   Pages 330-339 doi: 10.1007/s11705-019-1803-6

Abstract: Novel antibacterial materials for implants and medical instruments are essential to develop practical strategies to stop the spread of healthcare associated infections. This study presents the synthesis of multifunctional antibacterial nanocoatings on polydimethylsiloxane (PDMS) by remote plasma assisted deposition of sublimated chlorhexidine powders at low pressure and room temperature. The obtained materials present effective antibacterial activity against K12, either by contact killing and antibacterial adhesion or by biocide agents release depending on the synthetic parameters. In addition, these multifunctional coatings allow the endure hydrophilization of the hydrophobic PDMS surface, thereby improving their biocompatibility. Importantly, cell-viability tests conducted on these materials also prove their non-cytotoxicity, opening a way for the integration of this type of functional plasma films in biomedical devices.

Keywords： plasma polymers     conformal plasma deposition     chlorhexidine     bactericide     PDMS     biocompatibility    

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Shear-flexural strength mechanical model for the design and assessment of reinforced concrete beams subjected to point or distributed loads

Antonio MARÍ,Antoni CLADERA,Jesús BAIRÁN,Eva OLLER,Carlos RIBAS

Frontiers of Structural and Civil Engineering 2014, Volume 8, Issue 4,   Pages 337-353 doi: 10.1007/s11709-014-0081-0

Abstract: A mechanical model recently developed for the shear strength of slender reinforced concrete beams with and without shear reinforcement is presented and extended to elements with uniformly distributed loads, specially focusing on practical design and assessment in this paper. The shear strength is considered to be the sum of the shear transferred by the concrete compression chord, along the crack, due to residual tensile and frictional stresses, by the stirrups and, if they exist, by the longitudinal reinforcement. Based on the principles of structural mechanics simple expressions have been derived separately for each shear transfer action and for their interaction at ultimate limit state. The predictions of the model have been compared to those obtained by using the EC2, MC2010 and ACI 318-08 provisions and they fit very well the available experimental results from the recently published ACI-DAfStb databases of shear tests on slender reinforced concrete beams with and without stirrups. Finally, a detailed application example has been presented, obtaining each contributing component to the shear strength and the assumed shape and position of the critical crack.

Keywords： shear strength     mechanical model     reinforced concrete     design     assessment     shear tests    

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Effect of asphalt thin beams mixed with three nominal maximum aggregate sizes in the bending beam rheometer on the prediction of thermal properties of bituminous material

Chun-Hsing HO,María Francisca Martínez GONZÁLEZ,Cristina Pilar Martín LINARES

Frontiers of Structural and Civil Engineering 2017, Volume 11, Issue 1,   Pages 1-7 doi: 10.1007/s11709-016-0367-5

Abstract: The objective of this research is to evaluate an impact of asphalt mixture beams with varying sizes of aggregate in the Bending Beam Rheometer (BBR) for testing/predicting thermal cracking properties of asphalt pavements. The BBR test has following benefits: the equipment is cheaper, it uses smaller specimens, faster conditioning, easier availability for quality control, easier to manage, etc. However some concerns have been raised: some consider that the size of the aggregate may affect the test’s results; the other concern is that such small beams cannot represent the whole properties of the asphalt pavement. To address these criticisms, imaging techniques, statistical analysis, and viscoelastic modeling are used. Asphalt thin beams prepared with three different nominal maximum aggregate size (NMAS) (12.5mm, 9.5 mm, and 4.75 mm) were tested at three different temperatures (-18°C, -24°C, and -30°C). Based on results from statistical analyses and viscoelasticity, the ratio of asphalt binders and voids and stiffness differences among the three NMAS specimens are not significant, meaning that the impact of asphalt thin beams prepared with the three NMAS on the prediction of thermal cracking is minimal and can be neglected.

Keywords： bending beam rheometer     thin beams     thermal cracking    

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Transport of bacterial cell (

Wei Fan, Qi Li, Mingxin Huo, Xiaoyu Wang, Shanshan Lin

Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 4, doi: 10.1007/s11783-020-1242-0

Abstract: Abstract • The recharge pond dwelling process induced changes in cell properties. • Cell propertiesCommonly used recharge water resources for artificial groundwater recharge (AGR) such as secondary effluentThe dwelling process in recharge pond imposed physiologic stress on Escherichia coli (E. coli) cells,recharge water conditions, induced changes in cell properties.During adaptation to the recharge water environment, the zeta potential of cells became more negative

Keywords： Artificial groundwater recharge     E. coli     Transport     Simulated column experiments     Modeling    

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Multiplexed Biosensing Diagnostic Platforms Detecting Autoantibodies to Tumor-Associated Antigens from Exosomes Released by CRC Cells and Tissue Samples Showed High Diagnostic Ability for Colorectal Cancer Article

Ana Montero-Calle, Itziar Aranguren-Abeigon, María Garranzo-Asensio, Carmen Poves, María Jesús Fernández-Aceñero

Engineering 2021, Volume 7, Issue 10,   Pages 1393-1412 doi: 10.1016/j.eng.2021.04.026

Abstract:

Colorectal cancer (CRC) is the second leading cause of cancer related death worldwide. The 5-year survival rate of CRC patients depends on the stage at diagnosis, being higher than 80% when CRC is diagnosed in the early stages but lower than 10% when CRC is diagnosed in advanced stages. Autoantibodies against specific CRC autoantigens (tumor-associated antigens (TAAs)) in the sera of patients have been widely demonstrated to aid in early diagnosis. Thus, we herein aim to identify autoantigens target of autoantibodies specific to CRC that possess a significant ability to discriminate between CRC patients and healthy individuals by means of liquid biopsy. To that end, we examined the protein content of the exosomes released by five CRC cell lines and tissue samples from CRC patients by means of immunoprecipitation coupled with mass spectrometry analysis. A total of 103 proteins were identified as potential autoantigens specific to CRC. After bioinformatics and meta-analysis, we selected 15 proteins that are more likely to be actual CRC autoantigens in order to evaluate their role in CRC prognosis by Western blot (WB) and immunohistochemistry (IHC). We found dysregulation at the protein level for 11 of these proteins in both tissue and plasma exosome samples from patients, along with an association of nine of these proteins with CRC prognosis. After validation, all but one showed a statistically significant high diagnostic ability to distinguish CRC patients and individuals with premalignant lesions from healthy individuals, either by luminescence Halotag-based beads, or by a multiplexed biosensing platform involving the use of magnetic microcarriers as solid support modified with covalently immobilized Halotag fusion proteins constructed for CRC detection. Taken together, our results highlight the usefulness of the approach defined here to identify the TAAs specific to chronic diseases; they also demonstrate that the measurement of autoantibody levels in plasma against the TAAs identified here could be integrated into a point-of-care (POC) device for CRC detection with high diagnostic ability.

Keywords： Autoantibodies     Diagnosis     Colorectal cancer     Exosomes     Tumor microenviroment     Humoral immune response     Point of care     Biosensors    

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Assessment of oxidative and UV-C treatments for inactivating bacterial biofilms from groundwater wells

Kyle E. MURRAY,Erin I. Manitou-ALVAREZ,Enos C. INNISS,Frank G. HEALY,Adria A. BODOUR

Frontiers of Environmental Science & Engineering 2015, Volume 9, Issue 1,   Pages 39-49 doi: 10.1007/s11783-014-0699-0

Abstract: Disparity in the response to treatment was apparent in the wells despite their spatial proximity and common aquifer

Keywords： well rehabilitation     aquifer     biofouling     hydrogen peroxide     sustainability    

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Influence of reclaimed water discharge on the dissemination and relationships of sulfonamide, sulfonamide resistance genes along the Chaobai River, Beijing

Ning Zhang, Xiang Liu, Rui Liu, Tao Zhang, Miao Li, Zhuoran Zhang, Zitao Qu, Ziting Yuan, Hechun Yu

Frontiers of Environmental Science & Engineering 2019, Volume 13, Issue 1, doi: 10.1007/s11783-019-1099-2

Abstract: listitem>

SRGs and intI1 were widespread with high abundance after reclaimed water recharge

Keywords： Sulfonamide residues     Sulfonamide resistance genes     Reclaimed water recharge     Surface water     Class one integrons    

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Design, development, and performance of an ammonia self-managed vaporization propulsion system for micro-nano Regular Article

Shu-jian Sun, Tao Meng, Zhong-he Jin,sunshujian@zju.edu.cn,mengtao@zju.edu.cn

Frontiers of Information Technology & Electronic Engineering 2019, Volume 20, Issue 11,   Pages 1516-1529 doi: 10.1631/FITEE.1800068

Abstract: An ammonia propulsion (ASVP) system for s is presented. Compared with a normal cold gas or liquefied gas propulsion system, a multiplex parallel sieve type vaporizer and related vaporization control methods are put forward to achieve of liquefied propellant. The problems of high vaporization latent heat and incomplete vaporization of are solved, so that the ASVP system takes great advantage of high theoretical specific impulse and high propellant storage density. Furthermore, the ASVP operation procedure and its physical chemistry theories and mathematical models are thoroughly analyzed. An optimal strategy of thrust control is proposed with consideration of thrust performance and energy efficiency. The ground tests indicate that the ASVP system weighs 1.8 kg (with 0.34-kg propellant) and reaches a specific impulse of more than 100 s, while the power consumption is less than 10 W. The ASVP system meets multiple requirements including high specific impulse, low power consumption, easy fabrication, and uniform adjustable thrust output, and thus is suitable for s.

Keywords： 自主汽化管理；液氨；毫牛量级推进技术；微推力；高精度轨道控制；微纳卫星    

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Title Author Date Type Operation

Fifty Years of Water Sensitive Urban Design, Salisbury, South Australia

John C. Radcliffe, Declan Page, Bruce Naumann, Peter Dillon

Journal Article

Quantification of seepage in a multi-layered disconnected river-aquifer system

Jiang LI, Haizhu HU, Xiaomin MAO, Yi LIU

Journal Article

CHALLENGES PROVIDING MULTIPLE ECOSYSTEM BENEFITS FOR SUSTAINABLE MANAGED SYSTEMS

Journal Article

Nanosized magnetite in low cost materials for remediation of water polluted with toxic metals, azo- and antraquinonic dyes

María Fernanda HORST,Verónica LASSALLE,María Luján FERREIRA

Journal Article

Production of pectic extracts from sugar beet pulp with antiproliferative activity on a breast cancer cell line

Jacqueline CONCHA, Caroline WEINSTEIN, María Elvira Zú?IGA

Journal Article

The Fibrillar Matrix: Novel Avenues for Breast Cancer Detection and Treatment

Rasha Rezk,  Raquel Marín-García,  Annica K.B.Gad

Journal Article

Multifunctional antimicrobial chlorhexidine polymers by remote plasma assisted vacuum deposition

Aparicio, María Alcaire, Carmen López-Santos, Juan P.

Journal Article

Shear-flexural strength mechanical model for the design and assessment of reinforced concrete beams subjected to point or distributed loads

Antonio MARÍ,Antoni CLADERA,Jesús BAIRÁN,Eva OLLER,Carlos RIBAS

Journal Article

Effect of asphalt thin beams mixed with three nominal maximum aggregate sizes in the bending beam rheometer on the prediction of thermal properties of bituminous material

Chun-Hsing HO,María Francisca Martínez GONZÁLEZ,Cristina Pilar Martín LINARES

Journal Article

Transport of bacterial cell (

Wei Fan, Qi Li, Mingxin Huo, Xiaoyu Wang, Shanshan Lin

Journal Article

Multiplexed Biosensing Diagnostic Platforms Detecting Autoantibodies to Tumor-Associated Antigens from Exosomes Released by CRC Cells and Tissue Samples Showed High Diagnostic Ability for Colorectal Cancer

Ana Montero-Calle, Itziar Aranguren-Abeigon, María Garranzo-Asensio, Carmen Poves, María Jesús Fernández-Aceñero

Journal Article

Assessment of oxidative and UV-C treatments for inactivating bacterial biofilms from groundwater wells

Kyle E. MURRAY,Erin I. Manitou-ALVAREZ,Enos C. INNISS,Frank G. HEALY,Adria A. BODOUR

Journal Article

Influence of reclaimed water discharge on the dissemination and relationships of sulfonamide, sulfonamide resistance genes along the Chaobai River, Beijing

Ning Zhang, Xiang Liu, Rui Liu, Tao Zhang, Miao Li, Zhuoran Zhang, Zitao Qu, Ziting Yuan, Hechun Yu

Journal Article

Design, development, and performance of an ammonia self-managed vaporization propulsion system for micro-nano

Shu-jian Sun, Tao Meng, Zhong-he Jin,sunshujian@zju.edu.cn,mengtao@zju.edu.cn

Journal Article